Statins protect against Alzheimer’s in most patients
by Charles C. Chante MD - March 25, 2018 - 12:00am
Statins taken to reduce cholesterol also protect most patients against Alzheimer’s disease, but the decrease in risk varies across different statins and by the patient’s gender and race/ethnicity,...
For acute gout corticosteroids look safer than NSAIDs
by Charles C. Chante MD - March 18, 2018 - 12:00am
For the treatment of acute gout, corticosteroids maybe as effective as nonsteroidal anti-inflammatory drugs but with fewer side effects based on findings from a meta-analysis of six randomized, controlled trial...
High free-T4 levels linked to sudden cardiac death
by Charles C. Chante MD - March 11, 2018 - 12:00am
Higher levels of free thyroxine are associated with an increased risk of sudden cardiac death, even in euthyroid adults, according to a report published online in Circulation.
How to rule out secondary causes of osteoporosis
by Charles C. Chante MD - March 4, 2018 - 12:00am
Everyone diagnosed with osteoporosis deserves a laboratory assessment to rule out unsuspected secondary causes and a doozy of workup is recommended to primary physicians as “incredibly cost effective.&rdq...
Screen chronic opioids users for depression
by Charles C. Chante MD - February 25, 2018 - 12:00am
Depression combined with chronic opioid analgesic use involves more symptoms and comorbidities than depression without chronic opioid use, according to a study of Department of Veterans Affairs patients seen.
H. pylori’s relationship with gastric cancer? It’s complicated
by Charles C. Chante MD - February 18, 2018 - 12:00am
Does eradicating Helicobacter pylori prevent gastric cancer?
Hypertension med HCTZ linked to skin cancer risk
by Charles C. Chante MD - February 11, 2018 - 12:00am
Despite its widespread use as a guideline-recommended, first-line agent for the treatment of hypertension, hydrochlorothiazide may contribute to an increased risk of skin cancer, according to the division of dermatology,...
Physical activity found beneficial in NAFLD
by Sol Gorgonio - July 22, 2017 - 4:00pm
Regular physical exercise significantly improved measures of nonalcholic fatty liver disease (NAFLD), independently of dietary changes, according to a meta-analysis of randomized clinical trials.
CDC Confirms Link: Research shows Zika virus is a cause of microcephaly
by Charles C. Chante MD - May 6, 2017 - 9:05pm
Officials at the US Centers for Disease Control and Prevention have determined that Zika virus infection is a cause of microcephaly in babies born to infected mothers, following a systematic review of the latest...
Primary care acne
by Charles C. Chante MD - April 30, 2017 - 12:00am
If primary care physicians initiated therapy in patients with mild to moderate acne, they could significantly decrease referrals to dermatologists, reduce patient waiting times, and cut health care costs, a study...
Long-term PPI use tied to increased risk of dementia
by Charles C. Chante MD - April 23, 2017 - 12:00am
Long-term use of proton pump inhibitors was significantly associated with later diagnoses of dementia in adults aged 75 years and older in a prospective cohort study of more than 73,000 individuals.
Hormonal birth control does not induce VTE recurrence
by Charles C. Chante MD - April 16, 2017 - 12:00am
Hormonal contraceptives don’t appear to increase the risk of recurrence of venous thromboembolism among women taking anticoagulants, according to a report published in Blood.
High triglycerides tied to mortality in coronary heart disease
by Charles C. Chante MD - April 9, 2017 - 12:00am
Severe hypertriglyceridemia significantly increased the long term risk of death among patients with established coronary heart disease, even after low-density lipoprotein cholesterol was accounted for, according...
In obesity and knee osteoarthritis, weight loss is a big win
by Charles C. Chante MD - April 2, 2017 - 12:00am
Weight loss of more than five percent produced clinically meaningful improvements in knee osteoarthritis, even when final body mass index remained high, a large, community-based study has shown.
CDC updates guidelines for Zika virus testing, interpretation of results
by Charles C. Chante MD - March 26, 2017 - 12:00am
Patients with suspected Zika virus infection who have negative real-time reverse transcription-polymerase chain reaction test results are not automatically in the clear, officials at the Centers for Disease Control...
Chronic cough guideline highlights research needs
by Charles C. Chante MD - March 19, 2017 - 12:00am
Neuromodulatory therapies and speech pathology-based cough suppression are suggested treatment options for unexplained chronic cough in new guidelines from the CHEST Expert Cough Panel.
Prompt antidepressant treatment swiftly chopped cardiovascular risk
by Charles C. Chante MD - March 12, 2017 - 12:00am
Prompt, effective treatment for depression in the primary care setting appears to swiftly reduce the elevated cardiovascular risk known to be tied to the mood disorder, reported at the annual meeting of the American...
C. difficile raises risk of death, long-term care for seniors
by Charles C. Chante MD - March 5, 2017 - 12:00am
Clostridium difficile infections are a major driver of death and nursing home placement in Americans older than 65 years, according to research presented at a major international conference on infectious diseas...
Can aspirin prevent breast cancer?
by Charles C. Chante MD - February 26, 2017 - 12:00am
A large randomized controlled trial of aspirin for breast cancer prevention is warranted in light of new evidence that aspirin use shows a strong independent inverse relationship with mammographic breast density,...
Coronary artery calcium linked to cancer, kidney disease, pneumonia
by Charles C. Chante MD - February 19, 2017 - 12:00am
Patients whose coronary artery calcium scores exceeded 400 were significantly more likely to develop cancer, chronic obstructive pulmonary disease, chronic kidney disease, and hip fractures, compared with adults...
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