Gluten-free diet tied to heavy metal bioaccumulation
by Charles C. Chante MD - July 14, 2019 - 12:00am
A gluten-free diet was associated with significantly increased blood levels of mercury, lead, and cadmium and with significantly increased urinary levels of arsenic in a large cross-sectional; population-based survey...
COPD’s month of danger
by Charles C. Chante MD - July 7, 2019 - 12:00am
New use of inhaled long-acting beta, agonists or long-acting antimuscarinic antagonists was associated with a 1.5-fold increased cardiovascular risk within 30 days of initiation in patients with chronic obstructive...
Beware the COPD exacerbation
by Charles C. Chante MD - June 30, 2019 - 12:00am
A 70-year-old man with chronic obstructive pulmonary disease (COPD) is admitted with increased shortness of breath.
Online education linked to less anxiety in colonoscopy
by Charles C. Chante MD - June 23, 2019 - 12:00am
An online education program appeared to dampen anxiety levels in colonoscopy patients and even seemed to reduce the burden of the procedure in terms of time and medication used, a study showed.
NASH rapidly overtaking hepatitis C as cause of liver cancer
by Charles C. Chante MD - June 16, 2019 - 12:00am
Nonalcoholic steatohepatitis (NASH) is rapidly eclipsing hepatitis C virus (HCV) infection as the leading contributor to liver cancer in the United States.
Opioids linked to mortality in inflammatory bowel disease
by Charles C. Chante MD - June 9, 2019 - 12:00am
Among patients with inflammatory bowel disease, opioid prescriptions tripled during a recent 20-year period, and heavy use of strong opioids was significant predictor of all cause mortality, according to large cohort...
Overweight and obese patients face greater CV morbidity
by Charles C. Chante MD - June 2, 2019 - 12:00am
Obese individuals have shorter life spans and spend significantly more time dealing with the burden of cardiovascular morbidity than do normal-weight individuals, according to a US population-based study.
Serotonin syndrome risk with triptans and antidepressants very low
by Charles C. Chante MD - May 26, 2019 - 12:00am
The risk of serotonin syndrome developing in individuals who are taking both triptans for migraine and either an SSRI or serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant is very low, according to...
ACP sets higher ideal hemoglobin A range for type 2 diabetes
by Charles C. Chante MD - May 19, 2019 - 12:00am
Physicians should aim for hemoglobin A1C levels between 7% and 8% with type 2 diabetes, according to recommendations by the American College of Physicians.
ADA recommends cardioprotective antihyperglycemic drugs for patients
by Charles C. Chante MD - May 12, 2019 - 12:00am
Recent studies that confirm the cardiovascular benefit of some antihyperglycemic agents are shaping the newest therapeutic recommendations for patients with type 2 diabetes and co-morbid atherosclerotic cardiovascular...
Delayed HIV diagnosis still substantial for some at-risk groups
by Charles C. Chante MD - May 5, 2019 - 12:00am
HIV diagnoses are coming sooner after infection, increasing physicians’ ability to treat and prevent the spread of HIV, according to new Centers for Disease Control and Prevention Vital Signs report.
Up to 47 million Americans may have brain amyloidosis
by Charles C. Chante MD - April 28, 2019 - 12:00am
A treatment that cut the risk of developing amyloid plaques in the brain by 50 percent could save more than 4 million US residents from mild cognitive impairment and 2.5 million from Alzheimer’s disease by...
Low-sodium DASH benefit increases with higher blood pressures
by Charles C. Chante MD - April 21, 2019 - 12:00am
The low-sodium DASH diet lowered systolic BP mean of 20.8 mm Hg among patients with baseline systolic pressure of 150-159 mm Hg, and did so in just four weeks, according to a new analysis of the DASH-sodium tri...
Nebulized LABA found safe for long-term use in COPD
by Charles C. Chante MD - April 14, 2019 - 12:00am
No long term safety signals were seen in randomized trial that tested the formoterol fumurate inhalation solution against placebo in patients with moderate to severe chronic obstructive pulmonary disease.
Atrial fibrillation boosted VTE risk
by Charles C. Chante MD - April 7, 2019 - 12:00am
Atrial fibrillation is at least as strong a risk factor for venous thromboembolism as for ischemic stroke.
Hypertension guidelines aim to lower, reset threshold to 130/80 mm Hg
by Charles C. Chante MD - March 31, 2019 - 12:00am
Thirty million Americans became hypertensive overnight with the introduction of new high blood pressure guidelines from the American College of Cardiology and American Heart Association.
Revised guidelines raise lung cancer screening age
by Charles C. Chante MD - March 24, 2019 - 12:00am
A proposed change to CHEST’s lung cancer screening guidelines calls for raising the upper age for recent cigaret smokers to 77 years of age from 74 years of age.
Evidence builds for long-term ineffectiveness of steroid shots for knee OA
by Charles C. Chante MD - March 17, 2019 - 12:00am
Real-world, nontribal research confirms the findings of a high-profile study released earlier in 2017.
Knee osteoarthritis linked to premature mortality
by Charles C. Chante MD - March 10, 2019 - 12:00am
Knee osteoarthritis was independently associated with increased risk of premature mortality in the largest-ever meta-analysis to examine the issue, as reported at the World Congress on Osteoarthritis.
Initial HCV test results false positive in almost half of population
by Charles C. Chante MD - March 3, 2019 - 12:00am
Nearly half of patients in the general population who test positive for hepatitis C virus do not have the disease.
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