Diabetes – high rate of med discontinuation requires vigilance
by Charles C. Chante MD - August 18, 2019 - 12:00am
Most patients with type 2 diabetes mellitus stop taking their medication within a year, and nearly one-third stop within the first 3 months, a retrospective analysis of claims data for more than 324,000 patients...
ACIP unanimously recommends new hepatitis B vaccine
by Charles C. Chante MD - August 11, 2019 - 12:00am
At a meeting of the Center for Disease Control and Prevention’s advisory committee on immunization practices, members unanimously voted to include HEPLISAV-B on the ACIP list of recommended products to vaccinate...
Aspirin may protect against dementia in type 2 diabetes
by Charles C. Chante MD - August 4, 2019 - 12:00am
Daily low-dose aspirin reduce the incidence of dementia by more than one-third in patients with type 2 diabetes mellitus in the randomized JPAD 2 study.
Head injury linked to amyloid deposition decades later
by Charles C. Chante MD - July 28, 2019 - 12:00am
A history of head injury is associated with increased amyloid deposition in the brain, both globally and in the frontal cortex, according to PET imaging in 329 older adults without dementia.
Blood test approved for patients with concussions
by Charles C. Chante MD - July 21, 2019 - 12:00am
The Food and Drug Administration approved a new blood test on Feb. 14 – the Banyan Brain Trauma Indicator – for assessing patients with mild traumatic brain injuries, also known as concussions.
Gluten-free diet tied to heavy metal bioaccumulation
by Charles C. Chante MD - July 14, 2019 - 12:00am
A gluten-free diet was associated with significantly increased blood levels of mercury, lead, and cadmium and with significantly increased urinary levels of arsenic in a large cross-sectional; population-based survey...
COPD’s month of danger
by Charles C. Chante MD - July 7, 2019 - 12:00am
New use of inhaled long-acting beta, agonists or long-acting antimuscarinic antagonists was associated with a 1.5-fold increased cardiovascular risk within 30 days of initiation in patients with chronic obstructive...
Beware the COPD exacerbation
by Charles C. Chante MD - June 30, 2019 - 12:00am
A 70-year-old man with chronic obstructive pulmonary disease (COPD) is admitted with increased shortness of breath.
Online education linked to less anxiety in colonoscopy
by Charles C. Chante MD - June 23, 2019 - 12:00am
An online education program appeared to dampen anxiety levels in colonoscopy patients and even seemed to reduce the burden of the procedure in terms of time and medication used, a study showed.
NASH rapidly overtaking hepatitis C as cause of liver cancer
by Charles C. Chante MD - June 16, 2019 - 12:00am
Nonalcoholic steatohepatitis (NASH) is rapidly eclipsing hepatitis C virus (HCV) infection as the leading contributor to liver cancer in the United States.
Opioids linked to mortality in inflammatory bowel disease
by Charles C. Chante MD - June 9, 2019 - 12:00am
Among patients with inflammatory bowel disease, opioid prescriptions tripled during a recent 20-year period, and heavy use of strong opioids was significant predictor of all cause mortality, according to large cohort...
Overweight and obese patients face greater CV morbidity
by Charles C. Chante MD - June 2, 2019 - 12:00am
Obese individuals have shorter life spans and spend significantly more time dealing with the burden of cardiovascular morbidity than do normal-weight individuals, according to a US population-based study.
Serotonin syndrome risk with triptans and antidepressants very low
by Charles C. Chante MD - May 26, 2019 - 12:00am
The risk of serotonin syndrome developing in individuals who are taking both triptans for migraine and either an SSRI or serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant is very low, according to...
ACP sets higher ideal hemoglobin A range for type 2 diabetes
by Charles C. Chante MD - May 19, 2019 - 12:00am
Physicians should aim for hemoglobin A1C levels between 7% and 8% with type 2 diabetes, according to recommendations by the American College of Physicians.
ADA recommends cardioprotective antihyperglycemic drugs for patients
by Charles C. Chante MD - May 12, 2019 - 12:00am
Recent studies that confirm the cardiovascular benefit of some antihyperglycemic agents are shaping the newest therapeutic recommendations for patients with type 2 diabetes and co-morbid atherosclerotic cardiovascular...
Delayed HIV diagnosis still substantial for some at-risk groups
by Charles C. Chante MD - May 5, 2019 - 12:00am
HIV diagnoses are coming sooner after infection, increasing physicians’ ability to treat and prevent the spread of HIV, according to new Centers for Disease Control and Prevention Vital Signs report.
Up to 47 million Americans may have brain amyloidosis
by Charles C. Chante MD - April 28, 2019 - 12:00am
A treatment that cut the risk of developing amyloid plaques in the brain by 50 percent could save more than 4 million US residents from mild cognitive impairment and 2.5 million from Alzheimer’s disease by...
Low-sodium DASH benefit increases with higher blood pressures
by Charles C. Chante MD - April 21, 2019 - 12:00am
The low-sodium DASH diet lowered systolic BP mean of 20.8 mm Hg among patients with baseline systolic pressure of 150-159 mm Hg, and did so in just four weeks, according to a new analysis of the DASH-sodium tri...
Nebulized LABA found safe for long-term use in COPD
by Charles C. Chante MD - April 14, 2019 - 12:00am
No long term safety signals were seen in randomized trial that tested the formoterol fumurate inhalation solution against placebo in patients with moderate to severe chronic obstructive pulmonary disease.
Atrial fibrillation boosted VTE risk
by Charles C. Chante MD - April 7, 2019 - 12:00am
Atrial fibrillation is at least as strong a risk factor for venous thromboembolism as for ischemic stroke.
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