Charles C. Chante MD
Charles C. Chante MD
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Increased risk of death seen even in lower-risk PPI users
by Charles C. Chante MD - April 22, 2018 - 12:00am
Proton pump inhibitors are associated with a significantly higher risk of death than are H2 receptor antagonists, according to a five-year longitudinal cohort study.
Exercise topped NSAIDs for knee osteoarthritis
by Charles C. Chante MD - April 15, 2018 - 12:00am
After participating in an eight-week neuromuscular exercise therapy program, patients with mild to moderate knee osteoarthritis showed significantly greater symptomatic improvement at 12 months of follow up than...
Cannabis shows inconsistent benefits for pain, PTSD
by Charles C. Chante MD - April 8, 2018 - 12:00am
Chronic pain and posttraumatic stress disorder are among the top reasons given by patients seeking medical marijuana in states where it is legal, but there is little scientific evidence to support its value for...
Bilateral cellulitis on legs? think venous stasis dermatitis
by Charles C. Chante MD - April 1, 2018 - 12:00am
If a patient present with cellulitis on both legs, think venous stasis dermatitis, which is the no. 1 misdiagnosis of cellulitis and a frequent cause of unnecessary hospitalization for so-called “red leg”...
Statins protect against Alzheimer’s in most patients
by Charles C. Chante MD - March 25, 2018 - 12:00am
Statins taken to reduce cholesterol also protect most patients against Alzheimer’s disease, but the decrease in risk varies across different statins and by the patient’s gender and race/ethnicity,...
For acute gout corticosteroids look safer than NSAIDs
by Charles C. Chante MD - March 18, 2018 - 12:00am
For the treatment of acute gout, corticosteroids maybe as effective as nonsteroidal anti-inflammatory drugs but with fewer side effects based on findings from a meta-analysis of six randomized, controlled trial...
High free-T4 levels linked to sudden cardiac death
by Charles C. Chante MD - March 11, 2018 - 12:00am
Higher levels of free thyroxine are associated with an increased risk of sudden cardiac death, even in euthyroid adults, according to a report published online in Circulation.
How to rule out secondary causes of osteoporosis
by Charles C. Chante MD - March 4, 2018 - 12:00am
Everyone diagnosed with osteoporosis deserves a laboratory assessment to rule out unsuspected secondary causes and a doozy of workup is recommended to primary physicians as “incredibly cost effective.&rdq...
Screen chronic opioids users for depression
by Charles C. Chante MD - February 25, 2018 - 12:00am
Depression combined with chronic opioid analgesic use involves more symptoms and comorbidities than depression without chronic opioid use, according to a study of Department of Veterans Affairs patients seen.
H. pylori’s relationship with gastric cancer? It’s complicated
by Charles C. Chante MD - February 18, 2018 - 12:00am
Does eradicating Helicobacter pylori prevent gastric cancer?
Hypertension med HCTZ linked to skin cancer risk
by Charles C. Chante MD - February 11, 2018 - 12:00am
Despite its widespread use as a guideline-recommended, first-line agent for the treatment of hypertension, hydrochlorothiazide may contribute to an increased risk of skin cancer, according to the division of dermatology,...
Flu vaccine decreased hospitalizations in patients 50 and older
by Charles C. Chante MD - January 28, 2018 - 12:00am
The seasonal influenza vaccination reduced flu-related hospitalizations by 56.8 percent among people aged 50 and older during a recent flu season, a study showed.
ACP guideline: Keep blood pressure below 150 mm Hg in healthy elderly
by Charles C. Chante MD - December 23, 2017 - 4:00pm
Treat to lower a persistent systolic blood pressure of 150 mm Hg or more in patients aged 60 years or older who are otherwise healthy, the American College of Physicians recommended in a new guideline for managing...
Smell test reflects brain pathologies, risk of Alzheimer’s
by Charles C. Chante MD - December 9, 2017 - 4:00pm
A scratch – and sniff test that asks subjects to identify 40 odors and ranks olfaction is almost as powerful as a predictor of Alzheimer’s disease is a positive test of amyloid.
CDC Confirms Link: Research shows Zika virus is a cause of microcephaly
by Charles C. Chante MD - May 6, 2017 - 9:05pm
Officials at the US Centers for Disease Control and Prevention have determined that Zika virus infection is a cause of microcephaly in babies born to infected mothers, following a systematic review of the latest...
Primary care acne
by Charles C. Chante MD - April 30, 2017 - 12:00am
If primary care physicians initiated therapy in patients with mild to moderate acne, they could significantly decrease referrals to dermatologists, reduce patient waiting times, and cut health care costs, a study...
Long-term PPI use tied to increased risk of dementia
by Charles C. Chante MD - April 23, 2017 - 12:00am
Long-term use of proton pump inhibitors was significantly associated with later diagnoses of dementia in adults aged 75 years and older in a prospective cohort study of more than 73,000 individuals.
Hormonal birth control does not induce VTE recurrence
by Charles C. Chante MD - April 16, 2017 - 12:00am
Hormonal contraceptives don’t appear to increase the risk of recurrence of venous thromboembolism among women taking anticoagulants, according to a report published in Blood.
High triglycerides tied to mortality in coronary heart disease
by Charles C. Chante MD - April 9, 2017 - 12:00am
Severe hypertriglyceridemia significantly increased the long term risk of death among patients with established coronary heart disease, even after low-density lipoprotein cholesterol was accounted for, according...
In obesity and knee osteoarthritis, weight loss is a big win
by Charles C. Chante MD - April 2, 2017 - 12:00am
Weight loss of more than five percent produced clinically meaningful improvements in knee osteoarthritis, even when final body mass index remained high, a large, community-based study has shown.
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